In the Copa Chile match on May 11, 2025, Antofagasta secured a convincing 3-1 victory against Deportes Iquique at the Estadio Regional Calvo y Bascuñán. The home team demonstrated their dominance throughout the match, effectively controlling the game. Deportes Iquique struggled to respond, ultimately conceding three goals while managing to score only once. This outcome highlighted Antofagasta's strong performance and set a positive tone for their campaign in the tournament.